Difficult Vascular Access (DVA) is a Serious Clinical Challenge

Treatment delays for patients can lead to adverse outcomes1-4

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A Fast Clinical solution

The Arrow EZ-IO Intraosseous Vascular Access System

When every moment matters, it’s time to rethink DVA.

In a medical emergency, you may be ready but unfortunately some veins are not. The Arrow EZ-IO System supports your success by enabling fast5 access when you encounter patients with difficult vascular access.

The Arrow EZ-IO System provides immediate access via the intraosseous route5 for DVA cases that are emergent, urgent, or medically necessary, such as cardiac, shock, respiratory, and neurologic cases.

It provides a reliable bridge6 until longer-term vascular access can be established,7 with up to 48-hour dwell time.**

Can your DVA patients afford to wait for IV access?

It’s time to think of intraosseous (IO) access earlier.

In patients with DVA, central venous catheter (CVC) access and peripheral IV (PIV) access can take longer and are less likely to be successful when compared with IO:

Access at the Speed of Life

Important Notice to Customers:

Arrrow EZ-IO Intraosseous Vascular Access System products purchased from parties other than Teleflex, such as through brokers, independent distributors, or online marketplaces (sometimes referred to as the “gray market”), may be counterfeit, modified, beyond Teleflex’s recommended shelf life, or improperly stored or handled. Therefore, please be advised that Teleflex does not provide warranty coverage or customer support for such products purchased from any source except Teleflex or its authorized distributors.


  1. Donnino MW, Salciccioli JD, Howell MD, et al. BMJ. 2014;348:g3028.
  2. Gayet-Ageron A, Prieto-Merino D, Ker K, et al. Lancet. 2018;391(10116):125-132.
  3. Ferrer R, Martin-Loeches I, Phillips G, et al. Crit Care Med. 2014;42(8):1749-1755.
  4. Fonarow GC, Smith EE, Saver JL, et al. Circulation. 2011;123(7):750-758.
  5. Davidoff J, Fowler R, Gordon D, et al. JEMS. 2005;30(10):s20-s23. Research sponsored by Teleflex Incorporated.
  6. Leidel BA, Kirchhoff C, Bogner V, et al. Resuscitation. 2012;83(1):40-45.
  7. Dolister M, Miller S, Borron S, et al. J Vasc Access. 2013;14(3):216-224. Research sponsored by Teleflex Incorporated.
  8. Lee PJ, Lee C, Rattner P, et al. Crit Care Med. 2015;43(6):1233-1238.
  9. Ross EM, Mapp J, Kharod C, et al. Am J Disaster Med. Spring 2016;11(s):119-123.
  10. Costantino TG, Kirtz JF, Satz WA. J Emerg Med. 2010;39(4):462-467. doi:10.1016/j.jemermed.2009.02.004.

*Epinephrine administered in hospital cardiac arrest.

**The Arrow EZ-IO System is indicated for intraosseous access anytime in which vascular access is difficult to obtain in emergent, urgent or medically necessary cases for up to 24 hours. For patients ≥ 12 years old, the device may be extended for up to 48 hours when alternate intravenous access is not available or reliably established.

† Analysis limited to administration of tranexamic acid.Data captured until 3 hours had elapsed.

‡Door-to-needle time for tPA.

§Placement mean time is measured from package opening to confirmation of blood/marrow aspirate.

||All complications, including non-serious. Insertion sites were inspected 24 hours after initial placement.

¥ The measured time of each procedure began with arrival at patient’s side and concluded with fluid/medication delivery.

#Time measured is patient arrival to the first dose of epinephrine.

Rx Only.

CAUTION: Federal (USA) law restricts this device to sale by or on the order of a physician.

The Arrow EZ-IO Needle Set is Sterile, Single Use: Do not reuse, reprocess or re-sterilize. Reuse of device creates a potential risk of serious injury and/or infection which may lead to death. Refer to Instructions for Use for complete warnings, indications, contraindications, precautions, and potential complications.

Teleflex, the Teleflex logo, Arrow, and EZ-IO are trademarks or registered trademarks of Teleflex Incorporated or its affiliates, in the U.S. and/or other countries. All other trademarks or registered trademarks are the property of their respective owners. MC-008765Rev0.1
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