Arrow EZ-IO Intraosseous Vascular Access System

Do NOT use the powered EZ-IO Vascular Access System in the sternum.

The Arrow EZ-IO Intraosseous Vascular Access System from Teleflex is a fast, safe and effective solution in emergency situations. The EZ-IO System is indicated anytime vascular access is difficult to obtain in emergent, urgent, or medically necessary cases for up to 24 hours and provides peripheral venous access with central venous catheter performance.1-2*†

EZ-IO Clinical Education

EZ-IO Comfort Website

9058 EZ-IO Vascular Access Driver NA 1
9066-VC-005 EZ-Stabilizer Dressing NA 5
9079-VC-005 EZ-IO 45 mm Needle Set ≥40 kg 5 Needle Sets
9001-VC-005 EZ-IO 25 mm Needle Set ≥3 kg 5 Needle Set
9018-VC-005 EZ-IO 15 mm Needle Set 3-39 kg 5 Needle Sets


  • The EZ-IO System is Effective; 97% first-attempt access success rate3
  • The EZ-IO System is Safe; <1% serious complication rate4
  • The EZ-IO System is Fast; Achieves vascular access within 10 seconds5
  • The adult proximal humerus optimizes EZ-IO Intraosseous Vascular Access System infusion rates (avg. 5L/hour under pressure) with less medication required for patient pain management6**
  • Many fluids and medications that can be given via a peripheral IV can be given via the IO route using the same dose, rate, and concentration7-10
  • Six approved insertion sites: proximal humerus, proximal tibia, distal tibia
  • Blood samples for laboratory testing can be obtained via the IO route

Based on preclinical and clinical evidence comparing IO and venous or arterial sources a number of common laboratory values correlate well; other values show clinical similarity without statistically significant correlation. Caution should be exercised with their interpretation. Certain point of care (POC) analyzers have been studied with acceptable results. Check with your laboratory for IO specimen processing capabilities. For more information regarding IO laboratory analysis, refer to the publication Science and Fundamentals of Intraosseous Vascular Access, available at:

While the articles support intraosseous vascular access indications, claims and applications of Arrow EZ-IO Intraosseous Vascular Access System, readers should consult a physician and product labeling for proper indications, contraindications, warnings and precautions prior to use.

Potential complications may include local or systemic infection, hematoma, extravasations, or other complications associated with percutaneous insertion of sterile devices


  1. Hoskins SL, Nascimento P Jr., Lima RM, Espana-Tenorio, JM, Kramer GC. Pharmacokinetics of intraosseous and central venous drug delivery during cardiopulmonary resuscitation. Resuscitation 2011; doi:10.1016/j.resuscitation.2011.07.041. Research sponsored by Teleflex Incorporated. (preclinical study)

  2. Hoskins SL, Zachariah BS, Copper N, Kramer GC. Comparison of intraosseous proximal humerus and sternal routes for drug delivery during CPR. Circulation 2007; 116:II_993. Research sponsored by Teleflex Incorporated. (preclinical study)

  3. Cooper BR, Mahoney PF, Hodgetts TJ, Mellor A. Intraosseous access (EZ-IO) for resuscitation: UK military combat experience. JR Army Med Corps. 2008;153:314-6.
  4. Teleflex Internal Data on File 2014.

  5. Davidoff J, Fowler R, Gordon D, Klein G, Kovar J, Lozano M, Potkya J, Racht E, Saussy J, Swanson E, Yamada R, Miller L. Clinical evaluation of a novel intraosseous device for adults: prospective, 250-patient, multi-center trial. JEMS 2005;30(10):s20-3. Research sponsored by Teleflex Incorporated.

  6. Philbeck TE, Miller L J, Montez D, Puga T. Hurts so good; easing IO pain and pressure. JEMS 2010;35(9):58-69. Research sponsored by Teleflex Incorporated or its affiliates.
  7. Voigt J, Waltzman M, Lottenberg L. Intraosseous vascular access for in-hospital emergency use: A systematic clinical review of the literature and analysis. Pediatr Emerg Care 2012;28(2):185-998. Research sponsored by Teleflex Incorporated.

  8. Von Hoff DD, Kuhn JG, Burris HA, Miller LJ. Does intraosseous equal intravenous? A pharmacokinetic study. Am J Emerg Med 2008; 26: 31-8.

  9. Neumar RW, Otto CW, Link MS, et al. Adult advanced cardiovascular life support. 2010 American heart association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation 2010;122(suppl 3):S729-67. doi:10.1161/CIRCULATIONAHA.110.

  10. Monsieurs KG, Nolan JP, Bossaert LL et al.European Resuscitation Council Guidelines for Resuscitation 2015 Section 1. Executive summary. Resuscitation 2015;95: 1-80

*Compared to single lumen Central Venous Catheters (CVCs). Based on Adult Proximal Humerus EZ-IO insertion data. **Compared to EZ-IO System tibial insertion Consult with the laboratory to determine acceptability of IO blood specimens for analysis. Rx only Needle Vise is a trademark or registered trademark of Atrion Medical Products, Inc. Teleflex, Arrow, EZ-Connect, EZ-IO and EZ-Stabilizer are trademarks or registered trademarks of Teleflex Incorporated or its affiliates, in the U.S. and/or other countries. MCI-2017-0721