There are five chief sources of Central Line-Associated Bloodstream Infections (CLABSIs):
The ErgoPack™ System with ARROWg+ard Blue Plus® or Chlorag+ard® chlorhexidine-based catheters give you a comprehensive approach for helping to prevent each one.
The bacterial burden can be reduced drastically by using antiseptics such as ChloraPrep (a >0.5% chlorhexidine preparation with alcohol is a CDC 1A recommendation for prepping insertion sites) or BIOPATCH® (use of a chlorhexidine-impregnated sponge dressing for temporary short-term catheters is a CDC 1B recommendation).1 In at least one study, a 2 percent chlorhexidine solution was superior to a 70 percent isopropyl alcohol solution and 10 percent Povidone-iodine for reducing the incidence of IV device-related infections.2 Teleflex's® Arrow® brand central line kits are the only products with Hi-Lite Orange® ChloraPrep.
According to the 2011 CDC guidelines, 250,000 Catheter-Related Bloodstream Infections occur in the U.S. each year.1 It is estimated that each incident of CVC-associated bloodstream infection can cost between $34,508-$56,000.3
At least two studies prove that maximal barrier precautions significantly reduce the likelihood of bloodstream infection.5,6 For example, Raad et al. found that the chance of infection was 6.3 times higher without maximal barrier precautions.
As important as using maximal barrier precautions are, as soon as the drape, gown, mask and cap are in the trash can, the catheter is open to contamination. In a prospective study of short-term, non-cuffed CVCs used in patients in an ICU, Safdar and Maki reported that 26 percent of CVC-related bloodstream infections appear to be derived from internal lumen contamination.7
Despite the use of barrier protection and surface antiseptics, bacteria can still gain access to the subcutaneous tract. Chlorhexidine-based technology impregnated into a catheter's surface “preps” the subcutaneous tract with antimicrobials at the time of insertion, then continues to have an inhibitory effect in the subcutaneous tract. ARROWg+ard Blue PLUS central lines and Chlorag+ard® PICC feature chlorhexidine impregnated into both the exterior and interior catheter surfaces.
As many as 26 percent of central venous catheter related bloodstream infections appear to be derived from internal lumen contamination.7 This occurs through repeated access into the system and/or breaks in technique during which bacteria gain access to the internal lumens of the catheter. Antimicrobial catheters protected on their intraluminal surface have every lumen protected with chlorhexidine to significantly reduce colonization. ARROWg+ard Blue PLUS and Chlorag+ard® catheters are the only antimicrobial catheters that have catheter hub and extension line protection as well.
Hematogenous seeding occurs when bacteria attach to the catheter from a distant site. Antimicrobial catheters, such as ARROWg+ard and ARROWg+ard Blue Plus, have been shown effective at significantly reducing colonization of their surface.8,9