Ventilator Associated Pneumonia (VAP)

What is VAP?

Ventilator-associated pneumonia is a nosocomial pneumonia that develops more than 48 hours after endotracheal intubation. It is one of the most common infections acquired by adults and children in intensive care units (ICUs) and is a cause of significant patient morbidity and mortality, increased utilization of healthcare resources, and excess cost.1

Subglottic secretion removal: a VAP reduction strategy

During mechanical ventilation, secretions from the upper respiratory tract accumulate above the endotracheal tube cuff. Studies have shown that these secretions can seep past the cuff into the lower respiratory tract, increasing the incidence of ventilator acquired pneumonia.2 Drainage of subglottic secretions has been demonstrated to be an effective strategy in reducing early onset of VAP.3 The Society for Healthcare Epidemiology of America (SHEA) has provided recommendations for addressing the 3 most common mechanisms by which VAP develops: aspiration of secretions, colonization of the aerodigestive tract, and use of contaminated equipment.1 In fact, SHEA recommends the use of a cuffed endotracheal tube with inline or subglottic suctioning as a strategy to reduce VAP.1

The clinical challenge

The endotracheal tube chosen for initial intubation does not always allow for easy access to the valuable practice of removing subglottic secretions. That is why we created the Teleflex® ISIS® HVT Endotracheal Tube with an attachable suction line. This versatile design eliminates the need to be selective during initial intubation, increasing the number of patients who can be viable candidates for subglottic suctioning, a clinically proven strategy for VAP reduction.3

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  1. Coffin SE, Klompas M, Classen D, et al. Strategies to prevent ventilator-associated pneumonia in acute care hospitals. Infect Control Hosp Epidemiol. 2008;29(suppl 1):S31-S40.
  2. American Thoracic Society. Hospital–acquired pneumonia in adults: diagnosis, assessment of severity, initial antimicrobial therapy, and preventative strategies. A consensus statement. Am J Respir Crit Care Med. 1995;153:1711-1725.
  3. Dezfulian C, Shojania K, Collard HR, Kim HM, Matthay MA, Saint S. Subglottic secretion drainage for preventing ventilator-associated pneumonia: a meta-analysis. Am J Med. 2005;118:11-18.

Teleflex, HVT, ISIS and LMA are trademarks or registered trademarks of Teleflex Incorporated or its affiliates, in the U.S. and/or other countries. LA MC-001250