Intraosseous Access

Arrow EZ-IO Intraosseous Vascular Access System:
A Line of Defense in Emergency Situations

In any situation where intravenous access is difficult to obtain in emergent, urgent, or medically necessary cases, the Arrow EZ-IO Intraosseous Vascular Access System from Teleflex is a proven,1 fast,2* and effective3 solution.

The system is indicated for up to 24 hours and may be extended for up to 48 hours for patients ≥ 12 years old when alternate intravenous access is not available or reliably established. The EZ-IO System provides peripheral venous access with central venous catheter performance.4-5*†

The Proximal Humerus Advantage


Gain insights on:

  • Current hospital research
  • Clinical conditions for IO consideration
  • Landmarking and arm positioning for proximal humerus
  • Pain management for alert patients


Greater flow rate
Average flow rate of 6.3 L/hour under pressure for proximal humerus6*‡, 1 L/hour under pressure for proximal tibia**

Reach the heart with medication or fluid in three seconds view video 7*

Video Spotlight

See the Arrow EZ-IO System in action.

Cadaveric - Site Identification/ Insertion video image

Cadaveric - Site Identification/ Insertion (full video)

Alternative Arm Positioning video image

Alternative Arm Positioning

Fluoroscopic View of Flow video image

Fluoroscopic View of Flow

Positioning/Anatomy Dissected video image

Positioning/Anatomy Dissected

Subclavian Vein Flush video image

Subclavian Vein Flush

Animation - Site Identification/ Insertion video image

Animation - Site Identification/ Insertion (full video)

Arrow EZ-IO System Benefits

paper stack image


More than 90 published case studies or clinical trials,8 learn more

10 second image


Achieves vascular access within 10 seconds2

ninety seven percent image


97% first-attempt access success rate3


Can Your Patients Afford to Wait for IV Access?

It's time to think of intraosseous access earlier.

Procedure Time

comparision chart

The median procedure time for PIV access in DVA patients is 8.8 minutes. However, the average Arrow EZ-IO System procedure time is 5.0 minutes.10¥

Learn More

Download the EZ-IO System App

Rx Only.
CAUTION: Federal (USA) law restricts this device to sale by or on the order of a physician.
The Arrow EZ-IO Needle Set is Sterile, Single Use: Do not reuse, reprocess or re-sterilize. Reuse of device creates a potential risk of serious injury and/or infection which may lead to death. Refer to Instructions for Use for complete warnings, indications, contraindications, precautions, and potential complications.


  1. Dolister M, Miller S, Borron S, et al. Intraosseous vascular access is safe, effective and costs less than central venous catheters for patients in the hospital setting. J Vasc Access 2013;14(3):216-24. doi:10.5301/jva.5000130. Research sponsored by Teleflex Incorporated.
  2. Davidoff J, Fowler R, Gordon D, Klein G, Kovar J, Lozano M, Potkya J, Racht E, Saussy J, Swanson E, Yamada R, Miller L. Clinical evaluation of a novel intraosseous device for adults: prospective, 250-patient, multi-center trial. JEMS 2005;30(10):s20-3. Research sponsored by Teleflex Incorporated.
  3. Cooper BR, Mahoney PF, Hodgetts TJ, Mellor A. Intra-osseous access (EZ-IO) for resuscitation: UK military combat experience. J R Army Med Corps. 2007;153(4):314-316
  4. Hoskins SL, Nascimento P Jr., Lima RM, Espana-Tenorio, JM, Kramer GC. Pharmacokinetics of intraosseous and central venous drug delivery during cardiopulmonary resuscitation. Resuscitation 2011; doi:10.1016/j.resuscitation.2011.07.041. Research sponsored by Teleflex Incorporated. (preclinical study)
  5. Hoskins SL, Zachariah BS, Copper N, Kramer GC. Comparison of intraosseous proximal humerus and sternal routes for drug delivery during CPR. Circulation 2007; 116:II_993. Research sponsored by Teleflex Incorporated. (preclinical study)
  6. Puga T, Montez D, Philbeck T, Davlantes C. Adequacy of Intraosseous Vascular Access Insertion Sites for High‐Volume Fluid Infusion. Crit Care Med 2016; 44(12):143. Research sponsored by Teleflex Incorporated. Based on healthy volunteer study.
  7. Montez D, Puga T, Miller LJ, et al. Intraosseous infusions from the proximal humerus reach the heart in less than 3 seconds in human volunteers. Annals of Emergency Medicine. 2015;66(4S):S47. Research sponsored by Teleflex Incorporated.
  8. Data on file. Teleflex Incorporated 2019.
  9. Stein J, George B, River G, et al. Ultrasonographically guided peripheral intravenous cannulation in emergency department patients with difficult intravenous access: a randomized trial. Ann Emerg Med. 2009;54(1):33-40.
  10. Ross EM, Mapp J, Kharod C, et al. Time to Epinephrine in Out-of-Hospital Cardiac Arrest: A Retrospective Analysis of Intraosseous Versus Intravenous Access. Am J Disaster Med. Spring 2016;11(s):119-123.
* Based on Adult Proximal Humerus EZ-IO System insertion data
** Based on Adult Proximal Tibial data.
† Compared to single lumen Central Venous Catheters (CVCs)
‡ Based on 300mmHg of pressure
¥ The measured time of each procedure began with arrival at patient's side and concluded with fluid/medication delivery.
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Teleflex, the Teleflex logo, Arrow, EZ-Connect, EZ-IO and EZ-Stabilizer are trademarks or registered trademarks of Teleflex Incorporated or its affiliates, in the U.S. and/or other countries. MCI-2020-0755